Li, et al. evaluated the dynamic changes in plasma levels of miRNAs and cardiac troponin I (cTnI) of 35 acute myocardial infarction (AMI) patients and 55 matched controls, and found that the circulating level of miR-132-5p was maintained at a low level during the early phase of AMI and negatively correlated with cTnI. This evidence concerns the gene TNNI3 and acute myocardial infarction.