Furthermore, miR-124 participates in various neuroinflammation reactions; miR-124 inhibits neuroinflammation during the development of PD by regulating the MEKK3/NF-κB signaling pathways, suppressing neuroinflammation, and halting cell-cycle progression in activated encephalitogenic T cells in MS. Here, NFKB1 is linked to Parkinson disease.