PINK1 and neuroblastoma: In addition, Dagda et al. (2009) showed that transient expression of cleaved, cytosolic localized PINK1 (ΔN-PINK1) can mitigate macroautophagy induced by loss of PINK1 in human, undifferentiated SH-SY5Y neuroblastoma cells (Dagda et al., 2009; Fedorowicz et al., 2014; Lim et al., 2015).