An inverse association, and mutually exclusive expression of Bcl-2 and Mcl-1 was confirmed in a second cohort, and at the protein level, by IHC staining of a tissue microarray comprising 137 DLBCL samples for Mcl-1 and Bcl-2 (Fig. 3d, e). The gene discussed is BCL2; the disease is diffuse large B-cell lymphoma.