TIGIT and neoplasm: Cox regression model showed that high expression of TIGIT in tumor samples correlates with poor prognosis in KIRC (HR, 1.05, 95% CI 1.02–1.08), KIRP (HR, 1.14, 95% CI 1.06–1.22), LGG (HR, 1.18, 95% CI 1.01–1.36), UVM (HR, 1.2, 95% CI 1.04–1.38), and with favorable prognosis in BRCA (HR, 0.96, 95% CI 0.93–1), CECS (HR, 0.9, 95% CI 0.84–0.97), HNSC (HR, 0.95, 95% CI 0.91–0.98), SKCM (HR, 0.96, 95% CI 0.94–0.98) (Fig. 2A).