The top 20 FRG1 correlated genes (Supplementary Table S2), with rs cutoff ≥ 0.539, were used to generate the multivariate cox regression model using TCGA-LIHC (The Cancer Genome Atlas Liver Hepatocellular Carcinoma) and TCGA-CHOL (The Cancer Genome Atlas Cholangiocarcinoma) datasets. This evidence concerns the gene FRG1 and cancer.