FRG1 expression affected levels of GM-CSF (Granulocyte Macrophage colony stimulating factor), PLGF (Placental Growth Factor), PDGFA (Platelet Derived Growth Factor A) and CXCL1 (Chemokine (C-X-C motif) ligand 1), which are well known for their effect on tumor progression, chemotaxis, migration and invasion29–34. Here, PGF is linked to neoplasm.