Correlational analysis of fold change in gene expression between mouse and human datasets revealed that Il7r, Id3, and Tnfsf11 are commonly decreased and Ccl4, Lag3, Ascl2, Nkg7, and Spp1 are commonly increased in SLE and autoimmune chimeras (Supplementary Fig. 2). The gene discussed is ASCL2; the disease is systemic lupus erythematosus.