We then analyzed a publicly available scRNA-seq dataset of CTCL skin tumors62 to identify the main cell type overexpressing CXCL13. Ten clusters were annotated including tumor cells, CD4+ T cells (CD4), Tregs, CD8+ T cells (CD8), B & plasma cells (B&PC), macrophages (mac), dendritic cells (DC), stroma, vasculature (vasc), and keratinocytes (KC) (Supplementary Fig. 6a, b). Here, CD8A is linked to keratoconus.