ABHD5 and intestinal neoplasm: Strikingly, the nuclear translocation of YAP was dramatically increased in an ABHD5 gene dosage-dependent manner in intestinal tumours of ApcMin/+/Abhd5f/+/Cre+ and ApcMin/+/Abhd5f/f/Cre+ mice relative to control (ApcMin/+/Abhd5+/+/Cre+) mice (Fig. 4i).