We assessed plasma concentration of 24 putative sepsis mediators on day-1, including inflammatory markers (IL-1α, IL-1β, IL1-RA, IL-6, IL-10, IL-12, IL-15, IL-17, IL-33, IFN-γ, TNF-α, CD40L, HSP70, sFAS, sFAS ligand, sST2, granzyme, TRAIL, PAI1, and VEGF), chemokines (IL-8, MCP1), and adhesion molecules (sVCAM, sICAM). The gene discussed is IL1B; the disease is Sepsis.