domesticus, the strongest peak (chr4: 129.62–129.64 Mb) overlaps a gene-rich locus spanning Txlna, Ccdc28b, and Tmem234. Txlna is an interleukin 14 gene expressed in various tumor cells and involved in cell proliferation of hepatocellular carcinomas [41]. This evidence concerns the gene TMEM234 and hepatocellular carcinoma.