Next, they measured the RNA expression of six lncRNAs in the human brain from both the SN and cerebellum (9 PD and 8 HC) in human peripheral blood monocytic cells (PBMCs) (20 PD and 20 HC samples) and found that four out of six lncRNAs, SNCA-AS1, MAPT-AS1, AK127687 and AX747125, were detected in CSF-derived exosomes (2 HCs). Here, SNCA is linked to Parkinson disease.