SIN3A and Parkinson disease: The researchers also highlighted 2 circRNAs with upregulated (chr11:5225503–5226657: + , hsa_circ_0036353) and 8 with downregulated (hsa_circ_0000690, hsa_circ_0001535, hsa_circ_0001451, hsa_circ_0004870, hsa_circ_0000605, hsa_circ_0014606, hsa_circ_0001801, hsa_circ_0001772) expression and disclosed that source genes (HBB, SIN3A, FBXW7, ITGAL, SIN3A) of the highlighted circRNAs were predominantly linked to functions of homeostasis and oxidative stress response, indicating the central role of reactive oxidative stress and dyshomeostasis in PD [41].