As previously described, oncogenic alterations in ERBB2, FGFR, MET were found almost exclusively in the adenocarcinoma subtype (regardless of tumour location); On the other hand, EGFR and KRAS alterations as well as CCND1 amplification were found in tumours with both adenocarcinoma and squamous cell carcinoma histology. This evidence concerns the gene EGFR and neoplasm.