AGR2 and hepatocellular carcinoma: Similarly, to confirm the role of LINC01857 in HCC progression by controlling AGR2, AGR2 was overexpressed in HCC cells with silencing LINC01857 (all p<0.01) (Fig 5A), and HCC cell proliferation was potentiated (Fig 5B), but apoptosis was quenched (all p<0.01) (Fig 5C).