LINC01857 and hepatocellular carcinoma: To clarify the downstream molecular mechanism of HCC cell proliferation and apoptosis, the fractionation of nuclear and cytoplasmic RNA assay and FISH assay were performed, which verified that LINC01857 was mainly located at the cytoplasm (all p<0.01) (Fig 3A and 3B), illustrating that LINC01857 could influence HCC by regulating downstream genes through the ceRNA network.