HDAC11 and Miyoshi myopathy: We further identified a marked consistency of HDAC11 mRNA expression across MM disease states relative to MGUS in the interrogation of RNA-Seq from 65 patients with MGUS, 64 patients with smoldering MM, 177 patients with newly diagnosed MM, 343 patients with early relapsed/refractory MM (RRMM, 1–3 prior lines of therapy), and 146 patients with late RRMM (>3 lines of therapy) (Figure 4D).