Interrogation of a publicly available RNA expression data set (35) demonstrated that HDAC11 expression was significantly higher in plasma cells from individuals with monoclonal gammopathy of undetermined significance (MGUS) relative to healthy donors (Figure 4C; MGUS [n = 44] vs. healthy donors [n = 22], P < 0.0001). Here, HDAC11 is linked to monoclonal gammopathy.