GNRH1 and benign prostatic hyperplasia: In common, all the studies identified a wide variety of enzymes and proteins with  diverse functions to be present in the saliva of BPH, WBPH, and GRH (Konishi et al. 2009; Liu et al. 2016; Huang et al. 2016; Hattori et al. 2015; Miao et al. 2018b). Proteins involved in Ca2+-binding, ATP-binding, cytoskeletal, DNA- or RNA-binding, chromatin binding, transporters, apolipoproteins, ubiquitin, and heat shock proteins were also identified in the saliva (Liu et al. 2016).