We have not explored the role of miR-514a-3p and/or SHP-2 in regulating other events within the placenta, but given the reported roles for both SHP-2 and miR-514a-3p in invasion and apoptosis in cancer cells, it will be interesting to investigate whether miR-514a-3p/SHP-2 regulates these events in the placenta and indeed in other tissues. Here, PTPN11 is linked to cancer.