Thus, we adoptively transferred BMDM‐derived MMTs (BMDM‐MMT) into the macrophage‐malfunctioned Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice bearing LLC, where the BMDM‐MMT were generated in vitro by differentiating bone marrow cells into macrophages with macrophage colony‐stimulating factor (M‐CSF) followed by α‐SMA+ phenotype induction with TGF‐β1[8, 11, 28] in vitro (Figures S9 and S10, Supporting Information). This evidence concerns the gene TGFB1 and severe combined immunodeficiency.