ALCLs with DUSP22 rearrangement were more likely to show “doughnut” cell morphology with central nuclear pseudoinclusions and less likely to show large pleomorphic and/or multinucleated cells which have been reported to be more common in ALK-negative compared to ALK-positive ALCL but less often seen in ALCL with DUSP22 and TP63 rearrangements [1, 4]. The gene discussed is TP63; the disease is anaplastic large cell lymphoma.