But both drugs were capable of reducing the extent of inflammation with regard to microglia or cytokine release in different set-ups of an in vitro astrocyte-microglia co-culture model of inflammation, contributing to better understanding mechanisms of actions of LTG and TPM in epilepsy and BD, especially possible anti-inflammatory mechanisms that lead to the therapeutic effects of both drugs. Here, TNFSF14 is linked to Behcet disease.