To compare the transcriptional and chromatin accessibility states of normal (WT) and precancerous melanocytes (MC; harboring the BRAFV600E mutation and p53 lf mutation) to fully transformed melanoma (MA) cells, we generated a stable transgenic zebrafish line with fluorescently labeled melanocytes expressing mCherry driven by the melanocyte-specific melanocyte inducing transcription factor a (mitfa) promoter (Ceol et al. 2011; White et al. 2011; Kaufman et al. 2016). Here, TP53 is linked to melanoma.