In this study, in addition to constructing the prognostic model for LGG, we also identified four differentially expressed genes and found the significant association between the four genes and six immune cell types (macrophages.M1, T.cells.gamma.delta, T.cells.regulatory, neutrophils, T.cells.CD4.naive, and monocytes) which infiltrated in LGG tumor. Here, CD4 is linked to neoplasm.