EZH2 expression was significantly elevated in ectopic and eutopic endometrium from women with endometriosis compared with control endometrium (Colón-Caraballo et al., 2015; Brunty et al., 2021); nuclear SIRT1 expression was increased in those with endometriosis and endometriosis-associated ovarian cancer, not in case with ovarian cancer only (Teasley et al., 2020). This evidence concerns the gene SIRT1 and ovarian cancer.