Other studies have found that down-regulation of MEG8 hampers oxygen-glucose deprivation-induced endothelial cell viability, migration and angiogenesis in mouse brain microvessels by targeting the miR-130a-5p/vascular endothelial growth factor A (VEGFA) axis, which alleviates cerebral ischemia after stroke (Sui et al., 2020). The gene discussed is VEGFA; the disease is Cerebral ischemia.