Jian et al. showed that miR-30b-3p was overexpressed in glioma, and RECK could be up-regulated by inhibiting miR-30b-3p, thereby reducing the proliferation, migration and invasion of tumor cells and declining the protein levels of MMP-2 and MMP-9 (Jian et al., 2019). This evidence concerns the gene MMP9 and central nervous system cancer.