Over-expression of STEAP3 contributes to iron uptake and sustain iron storage in support of the proliferation of multiple cancer cells, including colorectal cancer (Barresi et al., 2016), pancreatic cancer (Yu et al., 2020), bladder cancer (Kim et al., 2016), etc. However, few studies have explored the roles of STEAP3 in prognosis as well as immune infiltration in LIHC. The gene discussed is STEAP3; the disease is urinary bladder cancer.