Treatment of human tumor cells with cell permeable Glo1 inhibitor pro-drug, S-p-bromobenzylglutathione cyclopentyl diester (BBGD)—which delivers the Glo1 competitive inhibitor, S-p-bromobenzylglutathione (Ki = 160 nM) into cells, increased the cellular concentration of MG, protein, and DNA adducts and induced apoptosis (8, 9). The gene discussed is GLO1; the disease is neoplasm.