Studies carried out by Rodriguez-Puyol et al. showed thatILK activationand inhibition are tightly linked to the development of chronic kidneydisease (CKD).17,18 In addition, α-parvin mayplay a critical role in the kidney development and function;19 thus, given its interaction with ILK, this proteinmay represent a potential target for the development of new drugsagainst CKD. The gene discussed is ILK; the disease is chronic kidney disease.