ILK inhibitionhas been widely related to disorganization of the actin cytoskeletonand polymerization, and this effect has been related to cancer biology.13,34 However, its selective adaptor/scaffolding activation has not beenwidely studied, and some studies propose that actin polymerizationrepresents a new and promising approach for the treatment of CKD.35,36 As such, we selected peptides 2 and 3 forfurther characterizations due to their ability to increase F-actinpolymerization. This evidence concerns the gene ILK and chronic kidney disease.