G6PC1 and Hyperinsulinemia: Oral pretreatment with PCA might counteract insulin resistance status partly through induction of AKT phosphorylation and mitigation of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) expression in dexamethasone (Dex)-induced hyperinsulinemia and insulin resistance in rats [132].