RPS6KA3 and breast cancer: However, RSK2 expression has no statistically significant relationship with other biological characters of breast cancer, including tumor size (pooled OR = 0.995, 95% CI: 0.77–1.28, Cochran’s Q test p = 0.43, I2 = 0.0%) (Figure 4D) and clinical stage (pooled OR = 1.09, 95% CI: 0.71–1.67, Cochran’s Q test p = 0.87, I2 = 0.0%) (Figure 4E).