Table 1 demonstrates that the serum level of APOA-1 was an independent prognostic factor for OS among patients with HCC (HR = 0.594, 95% CI = 0.419–0.842, p = 0.007). T stage (HR = 22.649,95% CI = 1.605–3.022, p < 0.001) and TNM staging (HR = 2.222, 95% CI = 1.603–3.081, p < 0.001) were independent prognostic factors for PFS among patients with HCC. The gene discussed is APOA1; the disease is hepatocellular carcinoma.