The expression of TLR2, TLR6 and TLR11 on CD4+ T cells, and TLR2, TLR4, and TLR6 on the major histocompatibility complex class II positive (MHCII+) APCs were significantly upregulated in the acute phase of GBS and EAN, while the expression of TLR1 was decreased and the secretion of IL-17A was enhanced (123). Here, TLR4 is linked to Guillain-Barre syndrome.