Although angiotensinogen is predominantly expressed in the proximal tubule (Kobori et al., 2001; Lantelme et al., 2002; Kamiyama et al., 2014), several studies have shown that the glomerular angiotensinogen levels are increased under pathophysiologic conditions, including diabetes (Ohashi et al., 2010; Eriguchi et al., 2016). Here, AGT is linked to diabetes mellitus.