To validate whether a correlation of EpCAM and BCL9/CTNNB1 exists in cancers, we analyzed the correlations of EpCAM and BCL9 as well as EpCAM and CTNNB1 in lung cancer, colon cancer, esophageal cancer, stomach cancer, head and neck cancer, and kidney cancer. Here, CTNNB1 is linked to malignant colon neoplasm.