EPCAM and cancer: Wnt/β-catenin was reported to inhibit T cell infiltration, and EpCAM depletion led to a decrease of Wnt/β-catenin expression (Yamashita et al., 2007; Spranger et al., 2015), so we explored the relationship between EpCAM expression and CD8+ T cells infiltration in cancers by a CIBERSORT analysis of tissues, and we found that they were inversely correlated (Figures 2G–J).