For Glo-1 enzymatic activity, the differences were observed in the patients with schizophrenia and healthy controls when the GG genotype was compared to TT genotype (t = 2.54, P = 0.015 in patients, t = 2.59, P = 0.014 in controls) and when the GG + GT genotype was compared with the TT genotype (t = 2.13, P = 0.036 in patients, t = 2.16, P = 0.034 in controls) (Figure 2F and Supplementary Table 4). This evidence concerns the gene GLO1 and schizophrenia.