While the phenotypic markers for granulocytes (CD11b+Ly6G+) and monocytes (CD11b+Ly6Chigh) are the same as their myeloid-derived suppressor cell (MDSC) counterparts, these cells are not immunosuppressive in B16 melanoma when compared to other tumor models enriched with MDSCs25,26. The gene discussed is ITGAM; the disease is neoplasm.