Since Apo-lipoprotein B (Apo B) participates in the cellular cholesterol uptake from cholesterol-rich lipoproteins14, single-nucleotide polymorphism (SNP) in Apo B gene could predict changes in hypercholesterolemia and subsequent oxidative, inflammatory, lipid and anthropometrics states15,16. The gene discussed is APOB; the disease is Hypercholesterolemia.