The absence of significant association between genotypes and allele of G and C − 11377 C > G of ADIPOQ gene and risk of T2D might be due to the following results: Differences in the ADIPOQ − 11377 G > C genotype distribution in the ethnic background, location of these SNPs on the ADIPOQ gene, as such SNP − 11377 C > G is located in the ADIPOQ gene promoter region, whereas + 276 G > T is located in the intron 2 region. Here, ADIPOQ is linked to type 2 diabetes mellitus.