Existing algorithms to detect late-onset placental dysfunction (UAD impedance and PlGF/sFlt1 ratio in maternal serum) [100] may be strengthened by inclusion of one or more of these miRNAs or combining miRNAs with recently identified circulating mRNA markers such as EMP1, which is increased in women who subsequently suffered a stillbirth [101]. The gene discussed is EMP1; the disease is urethra adenocarcinoma.