RELA and metabolic dysfunction-associated steatohepatitis: This finding is consistent with a previous study that demonstrated the anti-inflammatory function of EVs from amnion-derived MSCs (AmMSC-EV); AmMSC-EV suppressed the expression of LPS-stimulated inflammatory cytokines and chemokines in HFD-induced NASH rats as well as in Kupffer cells via inhibiting p65 phosphorylation and resulting NF-κB transcriptional activity [70].