Moreover, we examined XRCC1 mRNA expression in normal pancreatic tissue and pancreatic cancer (PAAD) tissues by interrogating 167 samples (GTEx normal), 4 tumor-adjacent tissues (TCGA), 179 carcinoma samples (TCGA) and the results showed that XRCC1 mRNA expression was significantly elevated in PAAD tissues relative to associated normal pancreatic tissue (Fig. 2B). The gene discussed is XRCC1; the disease is pancreatic neoplasm.