NQO1 and familial pancreatic carcinoma: For all four tested pancreatic cancer cell lines, cell death happened in an NQO1-dependent manner, as dicoumarol (DIC, an NQO1 inhibitor) treatment (Figs. 1B~ D) or S2–013 cells (NQO1-deficient cells, Fig. 1E) remained nonresponsive to β-lap, suggesting low NQO1 expression spared cells from lethality induced by β-lap.