FURIN and infection: Johnson et al. (2021) claimed that their results “demonstrate a critical role for the furin cleavage site in infection with SARS-CoV-2”. In ferrets infected with SARS-CoV-2 lacking the FCS, virus was shed at lower titers and not transmitted to cohoused ferrets in contrast to similar infection and transmission experiments with the wild type SARS-CoV-2 (Peacock et al. 2021).