LATS2 and central nervous system cancer: We found LATS2-methylated IDHmut-non-codel gliomas to be significantly enriched in young adults (FDR= 1.21E-13), while LATS2-methylated IDHmut-codel gliomas were suggestively enriched in later-onset cases (FDR = 0.100) (Figures 4C and S4C).