Conversely, somatic mutations of TP53 (FDR = 5.09E-3), FAT1 (FDR = 0.027), and NF1 (FDR = 5.71E-3) were significantly associated with later-onset CESC, HNSC (head and neck squamous cell carcinoma), and SKCM, respectively. This evidence concerns the gene TP53 and head and neck squamous cell carcinoma.