CYP2C9 and diabetes mellitus: It is also used as a botanical medicine to boost memory or to treat fatigue, menopause symptoms, and diabetes.25 Ginsenosides, the major active constituents of the root, have been studied for their antioxidants and antiproliferative effects.67 Drug interaction studies conducted in vitro have reported different results, yielding inconclusive data and suggesting only a weak interaction with the P450 cytochrome system, with a modest inhibition of CYP3A4, CYP1A2, CYP2C9, CYP2C19, and CYP2D6.