LZTR1 and infection: Besides, the analysis of the histological lymph node of ChAdOx1/MVA-NS1-NS2-Nt-immunized sheep showed that the LN architecture (data not shown) was preserved after BTV-4M infection, suggesting that this prime-boost immunization strategy not only promotes a faster viral clearance and reduction of the period and level of viremia but also protects from the pathology produced by a BTV infection in the natural host.