As it has been previously stated, the vaccine strategies ChAdOx1-NS1-NS2-Nt and ChAdOx1/MVA-NS1-NS2-Nt elicited protection in immunized sheep although they did not confer sterilizing immunity, which is not abnormal as long as CD8+ T cells do not prevent completely the infection because usually they recognize and respond to infected cells, but they can eventually outcome rapid virus clearance (71). This evidence concerns the gene CD8A and infection.