PTPRC and neoplasm: Moreover, genetic overactivation of sensory neurons led to a decrease in proliferating cells within the tumor (from 3050 ± 203 to 1292 ± 367 Ki67 + cells per μm2, analyzed by immunohistochemistry) (Fig. 3G, H), corroborated by flow cytometry analysis of CD45- cells for Ki67 expression (the was a decrease from 8.13 ± 1.00 to 5.07 ± 0.70% of CD45-/Ki67 + cells within the population of CD45- cells) (Fig. 3I).