To evaluate the role of sensory stimulation on tumor growth, we transplanted subcutaneously B16F10 melanoma cells to the lower right flank of both stimulatory DREADD-expressing mice (Nav1.8-Cre + /hM3Dq +) and their controls (Nav1.8-Cre-/hM3Dq +). Here, SCN10A is linked to melanoma.