Overall, the results among the Indian populations were found to be largely inconsistent with exception to a few SNPs—rs7903146 and rs12255372 of TCF7L2, rs2970847 of PGC-1α, rs9939609 of FTO, rs1801282 of PPARG, rs4402960 of IGF2BP2 and rs5219 of KCNJ11 [9–11, 19, 26–32] that showed a relatively greater degree of consistency in their association with T2DM. This evidence concerns the gene TCF7L2 and type 2 diabetes mellitus.