SHANK3 and acute lymphoblastic leukemia: Finally, neurological symptoms reminiscent of deficient motor skills (ex4-22|ALL [130], ex4-9|ANK [167, 200], ex11|SH3 [123], ex13-16|PDZ [140], ex13|PDZ [139, 176], ex21|PRO [179], ex21|PRO-InsG3680 [127]), abnormal sensory processing (ex4-22|ALL [92, 130], ex13-16|PDZ [140, 201], ex11-21|SH3-PRO rat [135]) or impaired cognitive capabilities (ex4-9|ANK [80, 167], ex13-16|PDZ [140, 188, 201], ex21|PRO [194], ex6|ANK rat [134]) described in PMDS patients were also present in some of the investigated heterozygous rodent models of SHANK3 deficiency.