The meta-analyses suggested that rFSH+rLH results in shorter stimulation length and fewer rFSH consumption,29and yields higher estradiol levels29, 30and higher number of mature oocytes.30While several meta-analysis showed no significant differences in implantation,2, 29, 30pregnancy,2, 29, 30and live-birth rates,2, 11, 30, 31others have demonstrated higher implantation rates,3pregnancy rates,3, 32ongoing pregnancy rates,11and lower miscarriage rates11in the recombinant LH-supplemented regimen. Here, PLOD1 is linked to spontaneous abortion.