The relevance of eosinophils and SIgA levels in the lung mucosa and their ability to control parasite burden was more evident in the re-infection model, as in contrast to high levels of total and A. suum antigen-specific SIgA levels (against antigens from adult worms and larvae of A. suum) in WT infected mice, the total and specific SIgA levels remained low in eosinophil-deficient mice (GATA1-/-) even after re-infection (Fig 8A). Here, GATA1 is linked to infection.