To better understand the impact of GC signaling on colorectal cancer development and progression, we analyzed the protein levels of GR in a colorectal cancer tissue microarray from a cohort of patients with colorectal cancer at the Fudan University Shanghai Cancer Center by immunohistochemical staining with an anti-GR antibody and scored the tissues based on the intensity and frequency of staining. The gene discussed is NR3C1; the disease is colorectal cancer.